Bullous Pesentation of Idiopathic Wells Syndrome (Eosinophilic Cellulitis).

نویسندگان

  • Charmaine E Lim
  • See Ket Ng
  • Steven Tg Thng
چکیده

Dear Editor, A 44-year-old female presented with pruritic oedematous papules and plaques with vesiculobullae formation over her face, trunk and limbs over 1 week (Fig. 1). She denied fever and other associated symptoms, drug intake, or insect bites. Her medical history was unremarkable. Complete blood count analysis revealed the presence of eosinophilia (0.81 x 109/L, normal 0.04-0.40 x 109/L). Levels of urea and electrolytes, and the results of liver function tests and chest radiography were normal. Antinuclear antibodies were absent, indicating that an autoimmune rheumatic disease was less likely. Stool specimens were negative for the presence of parasites. A skin biopsy was performed and histology findings were that of intense upper dermal oedema with subepidermal blister formation, and a dense superficial and deep perivascular and interstitial infiltrate of predominantly eosinophils with some lymphocytes (Figs. 2-4). Vessel walls were intact. Direct immunofluorescence revealed non-

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عنوان ژورنال:
  • Annals of the Academy of Medicine, Singapore

دوره 46 8  شماره 

صفحات  -

تاریخ انتشار 2017